Advances in Human Genetics 21 by Hugo W. Moser (auth.), Harry Harris, Kurt Hirschhorn (eds.)

By Hugo W. Moser (auth.), Harry Harris, Kurt Hirschhorn (eds.)

The present quantity contains chapters on peroxisomal problems, genetic elements of melanoma, Gaucher ailment, and different topics.

Show description

Read Online or Download Advances in Human Genetics 21 PDF

Similar genetics books

When I'm 164: The New Science of Radical Life Extension, and What Happens If It Succeeds

How lengthy do you need to reside, and why?

These are the questions that bestselling writer (Experimental guy) and technology author David Ewing Duncan explores, with striking effects. whilst I'm 164 surveys the more and more valid technological know-how of radical lifestyles extension—from genetics and regeneration to desktop solutions—and considers the pluses and minuses of dwelling to age 164, or past: every little thing from the effect on inhabitants and the price of dwelling to what occurs to like, interest, and health.

Concluding that anti-aging applied sciences will most likely achieve the following 30 to 50 years, Duncan brings us again to the age-old query posed via the Beatles of their vintage tune: Will you continue to desire me, will you continue to feed me, whilst I’m…

Small Molecule DNA And RNA Binders From Synthesis To Nucleic Acid Complexes Demeunynck

This ebook describes a robust and powerful software for the molecular biologist researcher. Readers will observe how DNA chromatography can be utilized of their personal paintings. meant as an creation for the molecular biologist reader, this also will function a realistic consultant for the skilled consumer. The transparent and concise writing sort can also be appealing to the chemist who desires to examine extra approximately molecular biology.

Origins of psychopathology: the phylogenetic and cultural basis of mental illness

Textual content covers psychiatry and evolutionary biology, psychopathology in the course of human organic evolution, and recapitulation and synthesis. Discusses if psychological affliction happens in primates and different animals, and if this is the case, what does this let us know approximately psychological disease in human evolution? writer is with Univ. of Pittsburgh, PA.

Extra resources for Advances in Human Genetics 21

Example text

1980), in the adrenal cortex by ACTH (Black and Russo, 1980), and by administration of thyroid hormone (Fringes and Reith, 1982). Peroxisome function thus is influenced by metabolic state, nutrition, and pharmaceutical agents in ways that have been studied only incompletely, but may prove relevant to the pathogenesis and treatment of peroxisomal disorders. Chapter 1: Peroxisomal Diseases 21 PEROXISOMAL DISORDERS Table I lists the genetically determined peroxisomal disorders that have been identified so far.

Induction of Peroxisome Proliferation Hess et al. (1965) were the first to show that hypolipemic agents such as clofibrate and industrial phthalate plasticizers resulted in proliferation of liver peroxisomes. This proliferation accounts for the striking liver enlargement produced by these agents in rodents. The administration of peroxisome proliferators has facilitated the study of peroxisome function: The initial demonstration that peroxisomes played a role in fatty acid ~-oxidation was conducted in clofibratetreated rats (Lazarow, 1978).

1964) and was assigned to the multiple congenital anomaly category. It represents the most severe prototype of a human peroxisome deficiency disorder, and affected children only rarely survive beyond the fourth month. Neonatal adrenoleukodystrophy (NALD) was TABLE I. Peroxisomal Disorders Disorders of peroxisome biogenesis Defects of single peroxisomal enzyme Multiple biochemical defects; peroxisome intact Zellweger syndrome Neonatal ALD Infantile Refsum disease Hyperpipecolic acidemia X-linked ALD Oxidase deficiency Bifunctional enzyme deficiency Thiolase deficiency Glutaryl CoA oxidase deficiency Acatalasemia Hyperoxaluria type 1 Rhizomelic chondrodysplasia punctata 22 Hugo W.

Download PDF sample

Rated 4.12 of 5 – based on 6 votes